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Parallel comprehensive two-dimensional gas chromatography
journal contribution
posted on 2017-11-17, 00:00 authored by DanDan Yan, Laura Tedone, Anthony Koutoulis, Simon P Whittock, Robert ShellieRobert ShellieWe introduce an information rich analytical approach called parallel comprehensive two-dimensional gas chromatography (2GC×2GC). This parallel chromatography approach splits injected samples into two independent two-dimensional column ensembles and provides two GC×GC separations by using contra-directional thermal modulation. The first-dimension (1D) and second-dimension (2D) columns are connected using planar three-port microchannel devices, which are supplied with supplementary flow via two pressure controller modules. Precise carrier gas flow control at the junction of the 1D and 2D columns permits independent control of flow conditions in each separation column. The 2GC×2GC approach provides two entirely independent GC×GC separations for each injection. Analysis of hop (Humulus lupulus L.) essential oils is used to demonstrate the capability of the approach. The analytical performance of each GC×GC separation in the 2GC×2GC experiment is comparable to individual GC×GC separation with matching column configurations. The peak capacity of 2GC×2GC is about 2 times than that of single GC×GC system. The dual 2D chromatograms produced by this single detector system provide complementary separations and additional identification information by harnessing different selectivity provided by the four separation columns.
History
Journal
Journal of chromatography aVolume
1524Pagination
202 - 209Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
0021-9673eISSN
1873-3778Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2017, Elsevier B.V.Usage metrics
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No categories selectedKeywords
2GC×2GCComprehensive two-dimensionalContra-directional modulationFlow controlGC×GCGas chromatographyChemistry Techniques, AnalyticalChromatography, GasOils, VolatilePressureScience & TechnologyLife Sciences & BiomedicinePhysical SciencesBiochemical Research MethodsChemistry, AnalyticalBiochemistry & Molecular BiologyChemistry2GC x 2GCGC x GCTHERMAL MODULATIONMASS SPECTROMETRYCOLUMNPERFORMANCESELECTIVITY
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