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Pharmacotherapy of bipolar disorder: the role of atypical antipsychotics and experimental strategies.

Version 2 2024-06-02, 13:16
Version 1 2015-03-18, 11:26
journal contribution
posted on 2024-06-02, 13:16 authored by GS Malhi, Michael BerkMichael Berk
Bipolar disorder, despite being a common and debilitating illness, has remarkably few pharmacological therapeutic options, the majority of which, with the exception of lithium, have been borrowed from other medical indications. Furthermore the quantity and quality of controlled clinical data are considerably smaller than in conditions of comparable severity and frequency. Not surprisingly, the clinical outcome of bipolar disorder is frequently suboptimal. Fortunately there are a growing number of novel therapeutic options for its treatment such as atypical antipsychotics, calcium channel blockers and omega-3 fatty acids. This paper summarizes some of the data regarding these "experimental" therapeutic options, focusing principally on atypical antipsychotics as these are now widely prescribed in the management of bipolar disorder.

History

Journal

Human Psychopharmacology

Volume

17

Pagination

407-412

Location

England

ISSN

1099-1077

eISSN

1099-1077

Language

eng

Publication classification

C4.1 Letter or note

Copyright notice

2002, Wiley

Issue

8

Publisher

Wiley