Phenylphenalenones from the Australian plant Haemodorum simplex
Version 2 2024-06-06, 04:50Version 2 2024-06-06, 04:50
Version 1 2023-03-07, 04:30Version 1 2023-03-07, 04:30
journal contribution
posted on 2023-03-07, 04:30 authored by DA Dias, DJ Goble, CA Silva, S UrbanChemical investigation of the Australian plant Haemodorum simplex resulted in the isolation of three new phenylphenalenones, haemodorone (10), haemodorol (11), and haemodorose (12), together with the previously reported compounds 5, dilatrin (6), and xiphidone (8). The first complete 2D NMR characterization for all of the compounds isolated, including several chemical shift reassignments for dilatrin (6), is reported. In addition this is one of the few reports to discuss the isolation of new phenylphenalenones from an Australian medicinal plant. The crude extract of both the bulbaceous and aerial components of the plant exhibited varying degrees of antibacterial, antifungal, and antiviral activity, and only the bulbs displayed potent cytotoxic activity. © 2009 American Chemical Society and American Society of Pharmacognosy.
History
Journal
Journal of Natural ProductsVolume
72Pagination
1075-1080Location
United StatesPublisher DOI
ISSN
0163-3864eISSN
1520-6025Language
enIssue
6Publisher
American Chemical Society (ACS)Usage metrics
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No categories selectedKeywords
AnimalsAntineoplastic Agents, PhytogenicAustraliaDrug Screening Assays, AntitumorInhibitory Concentration 50Leukemia P388MagnoliopsidaMiceMicrobial Sensitivity TestsMolecular StructurePhenalenesPlants, MedicinalPoliovirusSimplexvirusScience & TechnologyLife Sciences & BiomedicinePlant SciencesChemistry, MedicinalPharmacology & PharmacyLACHNANTHES-TINCTORIAPHENALENONE PIGMENTSXIPHIDIUM-CAERULEUMCOLOURING MATTERSDERIVATIVESHAEMOCORINChemical SciencesBiological SciencesMedical and Health Sciences
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