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Phenylphenalenones from the Australian plant Haemodorum simplex

journal contribution
posted on 2023-03-07, 04:30 authored by DA Dias, DJ Goble, CA Silva, S Urban
Chemical investigation of the Australian plant Haemodorum simplex resulted in the isolation of three new phenylphenalenones, haemodorone (10), haemodorol (11), and haemodorose (12), together with the previously reported compounds 5, dilatrin (6), and xiphidone (8). The first complete 2D NMR characterization for all of the compounds isolated, including several chemical shift reassignments for dilatrin (6), is reported. In addition this is one of the few reports to discuss the isolation of new phenylphenalenones from an Australian medicinal plant. The crude extract of both the bulbaceous and aerial components of the plant exhibited varying degrees of antibacterial, antifungal, and antiviral activity, and only the bulbs displayed potent cytotoxic activity. © 2009 American Chemical Society and American Society of Pharmacognosy.

History

Journal

Journal of Natural Products

Volume

72

Pagination

1075-1080

Location

United States

ISSN

0163-3864

eISSN

1520-6025

Language

en

Issue

6

Publisher

American Chemical Society (ACS)