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Positron detection in silica monoliths for miniaturised quality control of PET radiotracers

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journal contribution
posted on 2024-06-17, 19:13 authored by MD Tarn, D Maneuski, Richard AlexanderRichard Alexander, NJ Brown, V O'Shea, SL Pimlott, N Pamme, SJ Archibald
We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [(68)Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith.

History

Journal

Chemical communications

Volume

52

Pagination

7221-7224

Location

Milton, Eng.

Publisher DOI

Open access

  • Yes

ISSN

1359-7345

eISSN

1364-548X

Language

eng

Author URL

Publication classification

C Journal article, C1.1 Refereed article in a scholarly journal

Copyright notice

2016, Royal Society of Chemistry

Issue

45

Publisher

Royal Society of Chemistry

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    Keywords

    970108 Expanding Knowledge in the Information and Computing Sciences090303 Biomedical InstrumentationSchool of Engineering970103 Expanding Knowledge in the Chemical Sciences4003 Biomedical engineering

    Licence

    CC BY 4.0

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