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Potent new cell adhesion inhibitory compounds from the root of Trichilia rubra
journal contribution
posted on 1994-01-01, 00:00 authored by L L Musza, L M Killar, P Speight, S McElhiney, C J Barrow, A M Gillum, R CooperA series of seco-limonoids, with uncommon hemi ortho ester A-rings, was isolated from the root of Trichilia rubra. Their structures were determined by extensive spectroscopic studies. The five new and two previously known compounds were all found to be potent inhibitors of LFA-1:ICAM-1 mediated cell adhesion.
