Pre-clinical therapeutic development of a series of metalloporphyrins for Parkinson's disease
journal contribution
posted on 2024-09-20, 02:15 authored by LP Liang, J Huang, R Fulton, JN Pearson-Smith, BJ Day, M PatelPre-clinical therapeutic development of a series of metalloporphyrins for Parkinson's disease
History
Journal
Toxicology and Applied PharmacologyVolume
326Pagination
34-42Location
United StatesPublisher DOI
ISSN
0041-008XeISSN
1096-0333Language
enPublication classification
C1.1 Refereed article in a scholarly journalPublisher
Elsevier BVPublication URL
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Keywords
AntioxidantsDopamineDrug developmentMPTPOxidative stressPharmacokinetic analysis1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineAdministration, OralAnimalsAntiparkinson AgentsBehavior, AnimalBiological AvailabilityBiomarkersBlood-Brain BarrierBrainCapillary PermeabilityDisease Models, AnimalDrug DesignDrug Evaluation, PreclinicalHalf-LifeInjections, IntraperitonealMPTP PoisoningMaleMetalloporphyrinsMice, Inbred C57BLMotor ActivityNeuroprotective AgentsOxidative StressRotarod Performance Test
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