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Prefrontal structural correlates of cognitive control during adolescent development: a 4-year longitudinal study

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posted on 01.05.2014, 00:00 authored by Nandi VijayakumarNandi Vijayakumar, S Whittle, M Yücel, M Dennison, J Simmons, N B Allen
Maturation of cognitive control abilities has been attributed to the protracted structural maturation of underlying neural correlates during adolescence. This study examined the relationship between development of two forms of cognitive control (proactive and reactive control) and structural maturation of the ACC, dorsolateral pFC, and ventrolateral pFC (vlPFC) between early and mid adolescence using a longitudinal design. Adolescents (n = 92) underwent baseline assessments when they were 12 years old and follow-up assessments approximately 4 years later. At each assessment, structural MRI scans were acquired, and a modified Stroop task was performed. Results showed longitudinal improvements in reactive control between early and mid adolescence. Furthermore, magnitude of the improvement in proactive control was associated with reduced thinning of the right vlPFC across the sample, whereas the magnitude of the improvements in reactive control was associated with reduced thinning of the left ACC inmen alone. These findings suggest that individual differences in the maturation of ACC and vlPFC underlie the development of two distinct forms of cognitive control between early and mid adolescence as well as highlight sex differences in this relationship. © 2014 Massachusetts Institute of Technology.

History

Journal

Journal of cognitive neuroscience

Volume

26

Issue

5

Pagination

1118 - 1130

Publisher

MIT Press

Location

Cambridge, Mass.

ISSN

0898-929X

eISSN

1530-8898

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Copyright notice

2014, Massachusetts Institute of Technology