Deakin University
Browse

File(s) under permanent embargo

Prevalence of antibodies against foot-and–mouth disease virus in cattle in Kasese and Bushenyi districts in Uganda

journal contribution
posted on 2010-01-01, 00:00 authored by F N Mwiine, C Ayebazibwe, W Alaho-Mukani, Soren AlexandersenSoren Alexandersen, K Tjoernehoj
The aim of this study was to determine the seroprevalence and serotype-specificity of the circulating
antibodies against Foot-and-Mouth Disease Virus (FMDV) in cattle in K asese and Bushenyi districts in
Uganda. A total of 309 serum samples were collected and tested for antibodies against Non-Structural (NS) and
Structural Proteins (SP) using Ceditest® FMDV-NS and C editest® FMDV type O test kits. Seroprevalences
were much higher in Kasese in both tests (61 and 43%, respectively) than in Bushenyi (3 and 4% , respectively).
A high proportion of sera, that tested positive in the NSP test, were subjected to seven serotype specific
blocking ELISAs for antibodies against the seven FMDV serotypes (O, A, C, Asia 1, SAT 1, SAT 2 and SAT
3). The study showed presence of antibodies against four FMDV serotypes with decreasing magnitude as
follows: O> SAT 1> SAT 3/SAT 2. It is recommended to develop sampling schemes to include virus recovery
and identification, as well as to focus serum sampling on young unvaccinated stock.

History

Journal

International journal of animal and veterinary advances

Volume

2

Issue

3

Pagination

89 - 96

Publisher

Maxwell Science Publication

Location

Pakistan

ISSN

2041-2908

eISSN

2041-2908

Language

English

Publication classification

CN.1 Other journal article

Usage metrics

    Research Publications

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC