Prevention of recurrent fetal death in utero due to group B streptococcal chorioamnionitis

Maternal colonisation with group B Streptococcus (GBS) is a well recognised cause of neonatal sepsis.1 Colonisation of the infant at delivery results in invasive disease in 1–2% of neonates with a 5% mortality.2 Routine antenatal screening is recommended and prophylaxis offered to colonised women. We report a case of recurrent mid-trimester fetal death in utero, caused by GBS chorioamnionitis, and a subsequent successful pregnancy achieved with intermittent amoxicillin therapy from 12 weeks’ gestation.