kanwar-progresson-2017.pdf (1.67 MB)
Progress on azadirachta indica based biopesticides in replacing synthetic toxic pesticides
journal contribution
posted on 2017-05-01, 00:00 authored by Suman Chaudhary, Rupinder Kanwar, A Sehgal, David CahillDavid Cahill, Colin BarrowColin Barrow, R Sehgal, Jagat KanwarOver the years, extensive use of commercially available synthetic pesticides against phytophagous insects has led to their bioaccumulation in the environment causing increased resistance and reduction in soil biodiversity. Further, 90% of the applied pesticides enter the various environmental resources as a result of run-off, exposing the farmers as well as consumers of the agricultural produce to severe health issues. Therefore, growing attention has been given toward the development of alternate environmentally friendly pesticides/insecticides that would aid an efficient pest management system and also prevent chronic exposures leading to diseases. One such strategy is, the use of neem plant's (Binomial name: Azadirachta indica) active ingredients which exhibit agro-medicinal properties conferring insecticidal as well as immunomodulatory and anti-cancer properties. The most prominent constituent of neem is azadirachtin, which has been established as a pivotal insecticidal ingredient. It acts as an antifeedant, repellent, and repugnant agent and induces sterility in insects by preventing oviposition and interrupting sperm production in males. This review discusses, key neem pesticidal components, their active functional ingredients along with recent strategies on employing nanocarriers, to provide controlled release of the active ingredients and to improve their stability and sustainability.
History
Journal
Frontiers in plant scienceVolume
8Article number
610Pagination
1 - 13Publisher
Frontiers MediaLocation
Lausanne, SwitzerlandPublisher DOI
ISSN
1664-462XLanguage
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2017, The AuthorsUsage metrics
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Keywords
Azadirachta indicaagro-medicinal componentsazadirachtinbiopesticidenanocarrierspesticidessustained deliveryScience & TechnologyLife Sciences & BiomedicinePlant SciencesAzadirachtaindicaagro-medicinalcomponentsNEEM LEAF GLYCOPROTEINPROPHYLACTIC GROWTH-INHIBITIONMURINE EHRLICH CARCINOMAAGRICULTURAL HEALTHCANCER INCIDENCECELL-PROLIFERATIONSEED KERNELOILEXPOSURELIMONOIDSPlant Biology
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