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Recent developments of nanoparticle-delivered dosage forms for buccal delivery

Version 2 2024-06-04, 11:46
Version 1 2019-09-24, 10:25
journal contribution
posted on 2024-06-04, 11:46 authored by PHL Tran, Wei DuanWei Duan, TTD Tran
The improvement of mucoadhesive buccal formulations has attracted profound interest in recent years. Drug permeability and controlled drug release via this route of administration are still a concern for effective therapy, although various strategies have been proposed. Advanced developments in nanotechnology have been investigated with promising clinical applications. The incorporation of nanoparticles in dosage forms for buccal delivery not only ensures efficient delivery but also reduces side effects to biological systems. Many approaches have been suggested to load and deliver nanoparticles containing drugs to the buccal mucosa both in topical and systemic administrations. This paper describes recent advanced concepts to include nanoparticles in dosage forms with improving drug delivery or targeting. The classification and discussion of these technologies are aimed at providing an overview of current strategies for applying controlled drug delivery. All remarkable findings will encourage innovative nanoparticle-delivered dosage forms for buccal delivery in clinical applications.

History

Journal

International Journal of Pharmaceutics

Volume

571

Article number

ARTN 118697

Pagination

1 - 7

Location

Netherlands

ISSN

0378-5173

eISSN

1873-3476

Language

English

Publication classification

C1 Refereed article in a scholarly journal

Publisher

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