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Recent strategic developments in the use of superdisintegrants for drug delivery

Version 2 2024-06-04, 11:46
Version 1 2020-01-31, 14:36
journal contribution
posted on 2024-06-04, 11:46 authored by PHL Tran, TTD Tran
Improving drug bioavailability in the pharmaceutical field is a challenge that has attracted substantial interest worldwide. The controlled release of a drug can be achieved with a variety of strategies and novel materials in the field. In addition to the vast development of innovative materials for improving therapeutic effects and reducing side effects, the exploration of remarkable existing materials could encourage the discovery of diverse approaches for adapted drug delivery systems. Recently, superdisintegrants have been proposed for drug delivery systems as alternative approaches to maximize the efficiency of therapy. Although superdisintegrants are well known and used in solid dosage forms, studies on strategies for the development of drug delivery systems using superdisintegrants are lacking. Therefore, this study reviews the use of superdisintegrants in controlled drug release dosage formulations. This overview of superdisintegrants covers developed strategies, types (including synthetic and natural materials), dosage forms and techniques and will help to improve drug delivery systems.

History

Journal

Current pharmaceutical design

Volume

26

Pagination

701-709

Location

Sharjah, United Arab Emirates

ISSN

1381-6128

eISSN

1873-4286

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Issue

6

Publisher

Bentham Science

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