Recent trends in capillary and micro-chip electrophoretic instrumentation for field-analysis
Version 2 2024-06-04, 12:17Version 2 2024-06-04, 12:17
Version 1 2018-08-06, 10:10Version 1 2018-08-06, 10:10
journal contribution
posted on 2024-06-04, 12:17authored byM Zhang, SC Phung, P Smejkal, Rosanne GuijtRosanne Guijt, MC Breadmore
Technical advances in the development of field-deployable capillary and microchip electrophoretic instruments and reports of their deployment between 2013 and 2017 were reviewed. Strategies and considerations in the design of the injection, separation and detection hardware, chemistry and associated infrastructure were discussed from an in-field perspective, with portability, robustness and automation/“ease of use” featuring as key requirements. Integration of functionality is important for adequate in-field performance. Progress was made towards the use of multiple channel devices for increased throughput and/or resolving power, mixing devices for on-line/in-line sample derivatization, battery operation and temperature control. The strengths and weaknesses of the various approaches described in the literature are discussed from the perspective of in-field operation. An overview of the applications of the field electrophoretic instruments is provided, including environmental science and planetary investigation.