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Review on sperm sorting technologies and sperm properties toward new separation methods via the interface of biochemistry and material science
journal contribution
posted on 2019-09-01, 00:00 authored by R D Katigbak, Giovanni TurchiniGiovanni Turchini, S P de Graaf, Lingxue KongLingxue Kong, Ludovic Dumee© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Successful fertilization in mammals requires spermatozoa to efficiently traverse the female reproductive tract to meet the egg. This process naturally selects high quality sperm cells for fertilization, but when artificial reproductive technologies are used such as in vitro fertilization, intracytoplasmic sperm injection, or intrauterine insemination, other methods of sperm selection are required. Currently, technology enables sperm sorting based on motility, maturity as defined by zeta potential or hyaluronic acid binding site expression, absence of apoptotic factors, appropriate morphology, and even sex. This review summarizes current knowledge on all known methods of sperm cell sorting, compares their efficiency, and discusses the advantages and limitations of each technique. Scope for further refinement and improvement of current methods are discussed as is the potential to utilize a variety of materials to innovate new methods of sperm separation.
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Journal
Advanced BiosystemsVolume
3Issue
9Article number
1900079Pagination
1 - 16Publisher
WileyLocation
London, Eng.Publisher DOI
eISSN
2366-7478Language
engPublication classification
C1 Refereed article in a scholarly journalUsage metrics
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