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STin2 VNTR polymorphism is associated with comorbid tobacco use and mood disorders.
journal contribution
posted on 2015-02-01, 00:00 authored by M R Pizzo de Castro, S O Vargas Nunes, R L Guembarovski, C B Ariza, J M Oda, H O Vargas, L G Piccoli de Melo, M A Watanabe, Michael BerkMichael Berk, M MaesThere is a significant comorbidity between mood disorders and tobacco use disorder (TUD), which may be related to both genetic and environmental factors. Gene variants of the 5-HT transporter, such as STin2 VNTR (a variable number of tandem repeats in the functional serotonin transporter intron 2) may be associated with mood disorders and TUD.
History
Journal
Journal of Affective DisordersVolume
172Pagination
347 - 354Publisher
ElsevierLocation
Amsterdam , NetherlandsPublisher DOI
eISSN
1573-2517Language
ENGPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2015, ElsevierUsage metrics
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Categories
Keywords
Genetic polymorphismInflammationMood disordersOxidative stressSerotonin transporterTobacco use disorderScience & TechnologyLife Sciences & BiomedicineClinical NeurologyPsychiatryNeurosciences & NeurologySEROTONIN TRANSPORTER GENEMAJOR DEPRESSIVE DISORDEROBSTRUCTIVE PULMONARY-DISEASECIGARETTE-SMOKINGNICOTINE-DEPENDENCEBIPOLAR DISORDERFOLLOW-UPPSYCHIATRIC-DISORDERSSUICIDAL-BEHAVIORMENTAL-HEALTHRISK-FACTORPOPULATION