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Safe and effective use of lithium
journal contributionposted on 2013-02-01, 00:00 authored by G S Malhi, M Tanious, D Bargh, P Das, Michael BerkMichael Berk
Lithium has proven efficacy in the treatment of bipolar disorder, both for acute mania and long-term mood stabilisation and prophylaxis. It is also useful in combating treatment-resistant depression. Compared to other mood stabilisers, lithium has a favourable efficacy-tolerability balance. Lithium is underused due to active marketing of alternatives and concerns regarding adverse effects, tolerability, and the perception that regular monitoring is difficult.