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Sex Differences in Cardiac Adaptation to Distinct Modalities of Exercise: A Cardiac Magnetic Resonance Study
journal contribution
posted on 2023-05-18, 06:09 authored by CHANNA E MARSH, Hannah Thomas, LOUISE H NAYLOR, LAWRENCE G DEMBO, DANIEL J GREENPURPOSE: No previous study has described sex differences in chronic cardiac adaptation in response to distinct modalities of exercise training in humans. METHODS: Cardiac magnetic resonance imaging (1.5 T) was used to assess left ventricular (LV) outcomes in 78 untrained subjects (46F, 26 M; 26.1 ± 5.4 yr). Subjects underwent 3 months of closely supervised and monitored resistance (RES) and endurance (END) training, separated by a 3-month washout period. RESULTS: LV mass (LVM) increased in response to END in both sexes (females △3.98 ± 7.98 g, P = 0.002; males △5.99 ± 10.67 g, P = 0.005), whereas LV end-diastolic volume (EDV) increased in males (△7.48 ± 11.91 mL, P = 0.002) but not females (△1.54 ± 10.49 mL, P = 0.373). In response to RES, LVM and EDV did not increase in either sex. The proportion of subjects exhibiting a positive response to training (i.e., a change >0) for LVM and EDV did not differ between sexes for either training modality. CONCLUSION: Eccentric hypertrophy in response to END training was more apparent in males than females, whereas there were no notable cardiac changes between sexes for RES training. The proportion of low versus high responders to training was not sex specific for LVM or EDV in response to either commonly prescribed exercise training modality.
History
Journal
Medicine and Science in Sports and ExerciseVolume
53Pagination
2543-2552Location
Baltimore, Md.Publisher DOI
ISSN
0195-9131eISSN
1530-0315Language
engPublication classification
C1.1 Refereed article in a scholarly journalIssue
12Publisher
Lippincott, Williams & WilkinsUsage metrics
Categories
Keywords
AdultCross-Over StudiesCross-Sectional StudiesEndurance TrainingExerciseFemaleHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance ImagingMaleResistance TrainingSex FactorsClinical ResearchCardiovascularHeart DiseaseHuman Movement and Sports Science not elsewhere classifiedPublic Health and Health Services not elsewhere classifiedMedical Physiology not elsewhere classified
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