peeters-smokingdescreases-2004.pdf (187.19 kB)
Smoking decreases the duration of life lived with and without cardiovascular disease: a life course analysis of the Framingham Heart Study
journal contribution
posted on 2004-03-01, 00:00 authored by A A Mamun, Anna PeetersAnna Peeters, J Barendregt, F Willekens, W Nusselder, L BonneuxAIMS: To compare the burden of cardiovascular disease in terms of lifetime risk and life years lived with disease between smokers and non-smokers. METHODS AND RESULTS: We constructed multi-state life tables describing transitions through various cardiovascular diseases for 4723 smokers and non-smokers observed during 20 biannual observations in the Original Framingham Heart Study. Non-smokers live 8.66 (95% CI 7.61-9.63) (men) and 7.59 (95% CI 6.33-8.92) (women) years longer than smokers and more years free of cardiovascular disease: 6.22 (95% CI 5.09-7.30) years for males and 4.93 (95% CI 3.54-6.29) for females. But non-smokers spend more years with cardiovascular disease over the life course: 2.43 (95% CI 1.72-3.16) years for males and 2.66 (95% CI 1.87-3.38) years for females. The risk of cardiovascular disease before age 70 is higher among smokers, but over the entire lifecourse male non-smokers have higher risks of coronary heart disease, myocardial infarction, stroke and congestive heart failure, and female non-smokers have higher risks of coronary heart disease and congestive heart failure. CONCLUSION: Smoking, by shortening life, decreases both the probability and duration of cardiovascular disease throughout the life course. Non-smokers live many years longer and longer free of cardiovascular disease than smokers, but at the end of their life non-smokers will have lived longer with cardiovascular disease.
History
Journal
European heart journalVolume
25Issue
5Pagination
409 - 415Publisher
Oxford University PressLocation
Oxford, Eng.Publisher DOI
ISSN
0195-668XLanguage
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2004, ElsevierUsage metrics
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AdultAgedAged, 80 and overCardiovascular DiseasesEpidemiologic MethodsFemaleHumansLife ExpectancyMaleMiddle AgedSmokinglifestylemortalitycardiovascular diseaseScience & TechnologyLife Sciences & BiomedicineCardiac & Cardiovascular SystemsCardiovascular System & CardiologyHEALTH EXPECTANCYMORBIDITYSMOKERSNEDCOM, The Netherlands Epidermiology and Demography Compression of Morbidity Research Group
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