dwyer-spectrumof-2014.pdf (1.76 MB)
Spectrum of renal disease in diabetes
journal contribution
posted on 2014-09-01, 00:00 authored by Jessie Teng, Karen DwyerKaren Dwyer, Prue Hill, Emily See, Elif I Ekinci, George Jerums, Richard J MacIsaacThe spectrum of renal disease in patients with diabetes encompasses both diabetic kidney disease (including albuminuric and non-albuminuric phenotypes) and non-diabetic kidney disease. Diabetic kidney disease can manifest as varying degrees of renal insufficiency and albuminuria, with heterogeneity in histology reported on renal biopsy. For patients with diabetes and proteinuria, the finding of non-diabetic kidney disease alone or superimposed on the changes of diabetic nephropathy is increasingly reported. It is important to identify non-diabetic kidney disease as some forms are treatable, sometimes leading to remission. Clinical indications for a heightened suspicion of non-diabetic kidney disease and hence consideration for renal biopsy in patients with diabetes and nephropathy include absence of diabetic retinopathy, short duration of diabetes, atypical chronology, presence of haematuria or other systemic disease, and the nephrotic syndrome.
History
Journal
NephrologyVolume
19Issue
9Pagination
528 - 536Publisher
WileyLocation
London, Eng.Publisher DOI
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eISSN
1440-1797Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2014, Asian Pacific Society of NephrologyUsage metrics
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AERdiabetic kidney diseasediabetic nephropathyeGFRnon-diabetic kidney diseaserenal biopsyAdultAgedBiopsyComorbidityDiabetes MellitusDiabetic NephropathiesFemaleHumansKidneyKidney DiseasesMaleMiddle AgedPredictive Value of TestsPrognosisRisk FactorsYoung AdultScience & TechnologyLife Sciences & BiomedicineUrology & NephrologyGLOMERULAR-FILTRATION-RATEKIDNEY-DISEASEMICROSCOPIC HEMATURIACLINICAL PREDICTORSNEPHROPATHYPREVALENCEINSUFFICIENCYOUTCOMESCLASSIFICATION
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