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Spectrum of renal disease in diabetes

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Version 2 2024-06-03, 18:12
Version 1 2018-07-10, 10:50
journal contribution
posted on 2024-06-03, 18:12 authored by Jessie Teng, Karen M Dwyer, Prue Hill, Emily See, Elif I Ekinci, George Jerums, Richard J MacIsaac
The spectrum of renal disease in patients with diabetes encompasses both diabetic kidney disease (including albuminuric and non-albuminuric phenotypes) and non-diabetic kidney disease. Diabetic kidney disease can manifest as varying degrees of renal insufficiency and albuminuria, with heterogeneity in histology reported on renal biopsy. For patients with diabetes and proteinuria, the finding of non-diabetic kidney disease alone or superimposed on the changes of diabetic nephropathy is increasingly reported. It is important to identify non-diabetic kidney disease as some forms are treatable, sometimes leading to remission. Clinical indications for a heightened suspicion of non-diabetic kidney disease and hence consideration for renal biopsy in patients with diabetes and nephropathy include absence of diabetic retinopathy, short duration of diabetes, atypical chronology, presence of haematuria or other systemic disease, and the nephrotic syndrome.

History

Journal

Nephrology

Volume

19

Pagination

528-536

Location

London, Eng.

Open access

  • Yes

eISSN

1440-1797

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Copyright notice

2014, Asian Pacific Society of Nephrology

Issue

9

Publisher

Wiley