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Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition

journal contribution
posted on 2021-10-10, 00:00 authored by Feby SaviraFeby Savira, R Magaye, C V Scullino, B L Flynn, S M Pitson, D Anderson, D J Creek, Y Hua, X Xiong, L Huang, D Liew, C Reid, D Kaye, A R Kompa, B H Wang
Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition

History

Journal

Toxicology Letters

Volume

350

Pagination

133 - 142

Publisher

Elsevier

Location

Amsterdam, The Netherlands

Publisher DOI

ISSN

0378-4274

eISSN

1879-3169

Language

eng

Author URL

Publication classification

C1 Refereed article in a scholarly journal

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    Research Publications

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    Keywords

    ACCUMULATIONCARDIAC FIBROSISCARDIORENAL SYNDROMECERAMIDEDesl inhibitorDihydroceramide desaturase 1HYPERTROPHYINDOXYL SULFATEINDUCTIONLife Sciences & BiomedicineNATRIURETIC PEPTIDESNF-KAPPA-BOXIDATIVE STRESSScience & TechnologySphingolipidsToxicologyUremic toxinsDes1 inhibitor

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    All Rights Reserved

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