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Spiroquinazoline, a novel substance P inhibitor with a new carbon skeleton, isolated from Aspergillus flavipes
A novel substance P inhibitor, spiroquinazoline [1], was isolated from the fungus Aspergillus flavipes, which was originally obtained from soil. The structure of 1 was determined by analysis of spectroscopic data and 1 was shown to contain a new carbon skeleton containing a spiro-carbon center. Also isolated from the same culture extract were the new natural product, benzodiazepiedione [3], and the known compounds, acyl aszonalenin [4], N-benzoyl-L-phenylalaninol, and seven diketopiperazines.
History
Journal
Journal of natural productsVolume
57Issue
4Pagination
471 - 476Publisher
American Chemical SocietyLocation
Washington, D.C.Publisher DOI
ISSN
0163-3864Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
[1994, American Chemical Society]Usage metrics
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