turner-sustainedbutnot-1999.pdf (142.81 kB)
Sustained but not repeated acute elevation of cortisol impaired the luteinizing hormone surge, estrus, and ovulation in gilts
journal contribution
posted on 1999-09-01, 00:00 authored by Anne TurnerAnne Turner, P H Hemsworth, B J Canny, A J TilbrookWe tested the hypothesis that sustained and repeated acute elevation of cortisol would impair the LH surge, estrus, and ovulation in gilts. Cortisol was injected intramuscularly, to achieve a sustained elevation of plasma concentrations of cortisol, or intravenously, to achieve an acute elevation of plasma concentrations of cortisol. Control gilts received i.m. injections of oil and i.v. injections of saline. These treatments were administered to gilts (n = 6 per treatment) at 12-h intervals from Days 7 to 11 of the estrous cycle until after estrus ceased or until Day 27 or 28 of the estrous cycle, whichever came first. The repeated acute elevation of cortisol had no effect on the LH surge, estrus, or ovulation. In contrast, when the elevation of cortisol was sustained, the LH surge, estrus, and ovulation were inhibited. We conclude that cortisol is capable of direct actions to impair reproductive processes in female pigs but that plasma concentrations of cortisol need to be elevated for a substantial period for this to occur.
History
Journal
Biology of reproductionVolume
61Issue
3Pagination
614 - 620Publisher
Society for the Study of ReproductionLocation
New York, N.Y.Publisher DOI
Link to full text
ISSN
0006-3363Language
engPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
1999, Society for the Study of ReproductionUsage metrics
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