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The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes

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journal contribution
posted on 2012-11-19, 00:00 authored by J S J Chia, J L McRae, P J Cowan, Karen DwyerKaren Dwyer
Diabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosinergic axis in the pathogenesis of both T1D and T2D, with particular emphasis on the role of CD39 and CD73. © 2012 Joanne S. J. Chia et al.

History

Journal

Journal of Biomedicine and Biotechnology

Volume

2012

Pagination

1 - 7

Publisher

Hindawi Publishing Corporation

Location

New York, N.Y.

ISSN

1110-7243

eISSN

1110-7251

Language

eng

Publication classification

C4.1 Letter or note