The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes
Version 2 2024-06-03, 18:13
Version 1 2018-07-10, 10:45
journal contribution
posted on 2012-11-19, 00:00 authored by J S J Chia, J L McRae, P J Cowan, Karen DwyerKaren DwyerDiabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosinergic axis in the pathogenesis of both T1D and T2D, with particular emphasis on the role of CD39 and CD73. © 2012 Joanne S. J. Chia et al.
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Journal
Journal of Biomedicine and BiotechnologyVolume
2012Pagination
1 - 7Publisher
Hindawi Publishing CorporationLocation
New York, N.Y.Publisher DOI
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1110-7243eISSN
1110-7251Language
engPublication classification
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Science & TechnologyLife Sciences & BiomedicineBiotechnology & Applied MicrobiologyMedicine, Research & ExperimentalResearch & Experimental MedicineISCHEMIA-REPERFUSION INJURYMEDIATED TISSUE PROTECTIONADENOSINE-RECEPTORT-CELLSINSULIN-RESISTANCEEXTRACELLULAR ATPGLUCAGON-SECRETIONA(2B) RECEPTORSBETA-CELLSTREG CELLS
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