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The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2009 on the treatment of acute mania

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journal contribution
posted on 2009-01-01, 00:00 authored by Heinz Grunze, Eduard Vieta, Guy M Goodwin, Charles Bowden, Rasmus W Licht, Hans-Jurgen Moller, Siegfried Kasper, H Akiskal, J L Ayuso-Gutierrez, M Bauer, P Bech, Michael BerkMichael Berk, I Bitter, G Burrows, J Calabrese, G Cassano, M Cetkovich-Bakmas, J C Cookson, I N Ferrier, W F Gattaz, F K Goodwin, G Heinze, T Higuchi, R M Hirschfeld, C Hoeschl, E Holsboer-Trachsler, K Redfield Jamison, C Katona, M Keller, E Kostukova, H Kruger, P Kulhara, Y Lecruibier, V Larach
These updated guidelines are based on a first edition that was published in 2003, and have been edited and updated with the available scientific evidence until end of 2008. Their purpose is to supply a systematic overview of all scientific evidence pertaining to the treatment of acute mania in adults. The data used for these guidelines have been extracted from a MEDLINE and EMBASE search, from the clinical trial database, from recent proceedings of key conferences, and from various national and international treatment guidelines. Their scientific rigor was categorised into six levels of evidence (A-F). As these guidelines are intended for clinical use, the scientific evidence was finally asigned different grades of recommendation to ensure practicability.



World journal of biological psychiatry






85 - 116


Taylor & Francis


Abingdon, Eng.





Publication classification

C1.1 Refereed article in a scholarly journal

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2009, Informa UK Ltd. (Informa Healthcare, Taylor & Francis AS)