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The effect of functional gastrointestinal disorders on psychological comorbidity and quality of life in patients with inflammatory bowel disease
journal contribution
posted on 2008-08-01, 00:00 authored by Antonina Mikocka-WalusAntonina Mikocka-Walus, D A Turnbull, J M Andrews, N T Moulding, G J HoltmannBACKGROUND: Symptoms of functional gastrointestinal disorders (FGIDs) are common in patients with inflammatory bowel disease (IBD). Psychological comorbidities of anxiety and depression are also highly prevalent in IBD. AIM: To quantify the burden of FGIDs in a hospital-based cohort of patients with IBD and to determine whether there is any inter-relationship between the presence and number of FGIDs and patients' quality of life or psychological status. METHODS: A cross-sectional survey of 61 out-patients was performed. Data on psychological status, quality of life, disease activity and functional symptoms according to Rome III criteria were collected. RESULTS: Overall, 49 (80%) participants met Rome III criteria for a functional bowel disorder and 52% of participants met criteria for more than one FGID. Participants with no FGID had significantly better physical quality of life than those with more than two FGIDs (P = 0.025). However, there was no relationship among the number of FGIDs, mental quality of life, anxiety or depression. CONCLUSIONS: Functional gastrointestinal disorders are highly prevalent in out-patients with IBD. Somewhat unexpectedly, the presence of anxiety and/or depression did not appear to correlate with either the presence or the number of FGIDs.
History
Journal
Alimentary pharmacology and therapeuticsVolume
28Issue
4Pagination
475 - 483Publisher
Wiley-Blackwell PublishingLocation
Chichester, Eng.Publisher DOI
ISSN
0269-2813eISSN
1365-2036Language
engPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
2008, The AuthorsUsage metrics
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No categories selectedKeywords
AdultAgedAged, 80 and overAnxiety DisordersDepressive DisorderFemaleHumansInflammatory Bowel DiseasesMaleMiddle AgedQuality of LifeSurveys and QuestionnairesScience & TechnologyLife Sciences & BiomedicineGastroenterology & HepatologyPharmacology & PharmacyFORM HEALTH SURVEYIBS-LIKE SYMPTOMSROME-IIHOSPITAL ANXIETYPREVALENCEIMPACTPOPULATIONDEPRESSIONREMISSIONCRITERIA
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