baguley-effectofnutrition-2017.pdf (7.37 MB)
The effect of nutrition therapy and exercise on cancer-related fatigue and quality of life in men with prostate cancer: a systematic review
journal contribution
posted on 2017-09-01, 00:00 authored by Brenton BaguleyBrenton Baguley, Kate Bolam, Olivia Wright, Tina SkinnerBackground: Improvements in diet and/or exercise are often advocated during prostate cancer treatment, yet the efficacy of, and optimal nutrition and exercise prescription for managing cancer-related fatigue and quality of life remains elusive. The aim of this study is to systematically review the effects of nutrition and/or exercise on cancer-related fatigue and/or quality of life. Methods: A literature search was conducted in six electronic databases. The Delphi quality assessment list was used to evaluate the methodological quality of the literature. The study characteristics and results were summarized in accordance with the review’s Population, Intervention, Control, Outcome (PICO) criteria. Results: A total of 20 articles (one diet only, two combined diet and exercise, and seventeen exercise only studies) were included in the review. Soy supplementation improved quality of life, but resulted in several adverse effects. Prescribing healthy eating guidelines with combined resistance training and aerobic exercise improved cancer-related fatigue, yet its effect on quality of life was inconclusive. Combined resistance training with aerobic exercise showed improvements in cancer-related fatigue and quality of life. In isolation, resistance training appears to be more effective in improving cancer-related fatigue and quality of life than aerobic exercise. Studies that utilised an exercise professional to supervise the exercise sessions were more likely to report improvements in both cancer-related fatigue and quality of life than those prescribing unsupervised or partially supervised sessions. Neither exercise frequency nor duration appeared to influence cancer-related fatigue or quality of life, with further research required to explore the potential dose-response effect of exercise intensity. Conclusion: Supervised moderate-hard resistance training with or without moderate-vigorous aerobic exercise appears to improve cancer-related fatigue and quality of life. Targeted physiological pathways suggest dietary intervention may alleviate cancer-related fatigue and improve quality of life, however the efficacy of nutrition management with or without exercise prescription requires further exploration.
History
Journal
NutrientsVolume
9Issue
9Article number
1003Pagination
1 - 30Publisher
MDPILocation
Basel, SwitzerlandPublisher DOI
Link to full text
eISSN
2072-6643Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2017, the authorsUsage metrics
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NutritionExerciseProstate cancerCancer-related fatigueQuality of lifeScience & TechnologyLife Sciences & BiomedicineNutrition & DieteticsANDROGEN-DEPRIVATION THERAPYRANDOMIZED CONTROLLED-TRIALSURVIVORS CURRENT GUIDELINESPHYSICAL-ACTIVITY GUIDELINESLONG-TERM SURVIVORSAEROBIC EXERCISEWEIGHT-LOSSFUNCTIONAL PERFORMANCESUPPRESSION THERAPYRESISTANCE EXERCISE
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