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The effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on longer-term maternal and early childhood outcomes: protocol for an individual participant data (IPD) meta-analysis
journal contribution
posted on 2017-03-09, 00:00 authored by Jodie M Dodd, Rosalie M Grivell, Jennie Louise, Andrea R Deussen, Lynne Giles, Ben W Mol, Christina Vinter, Mette Tanvig, Dorte Moller Jensen, Annick Bogaerts, Roland Devlieger, Riitta Luoto, Fionnuala McAuliffe, Kristina Renault, Emma Carlsen, Nina Geiker, Lucilla Poston, Annette Briley, Shakila Thangaratinam, Ewelina Rogozinska, Julie OwensBACKGROUND: The aim of this individual participant data meta-analysis (IPDMA) is to evaluate the effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood outcomes at ages 3-5 years. METHODS/DESIGN: We will build on the established International Weight Management in Pregnancy (i-WIP) IPD Collaborative Network, having identified researchers who have conducted randomised dietary and lifestyle interventions among pregnant women who are overweight or obese, and where ongoing childhood follow-up of participants has been or is being undertaken. The primary maternal outcome is a diagnosis of maternal metabolic syndrome. The primary childhood outcome is BMI above 90%. We have identified 7 relevant trials, involving 5425 women who were overweight or obese during pregnancy, with approximately 3544 women and children with follow-up assessments available for inclusion in the meta-analysis. DISCUSSION: The proposed IPDMA provides an opportunity to evaluate the effect of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood health outcomes, including risk of obesity. This knowledge is essential to effectively translate research findings into clinical practice and public health policy. SYSTEMATIC REVIEW REGISTRATION: This IPD has been prospectively registered (PROSPERO), ID number CRD42016047165 .
History
Journal
Systematic reviewsVolume
6Article number
51Pagination
1 - 12Publisher
BMCLocation
London, Eng.Publisher DOI
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eISSN
2046-4053Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2017, The Author(s)Usage metrics
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No categories selectedKeywords
Childhood obesityIndividual participant data meta-analysisPregnancy lifestyle interventionDietFemaleHumansLife StyleMaternal HealthObesityPediatric ObesityPregnancyPregnancy ComplicationsPregnancy OutcomeSystematic Reviews as TopicScience & TechnologyLife Sciences & BiomedicineMedicine, General & InternalGeneral & Internal MedicineGESTATIONAL WEIGHT-GAINBODY-MASS INDEXPATIENT DATASYSTEMATIC REVIEWSPHYSICAL-ACTIVITYRISKRETENTIONASSOCIATIONSPREVALENCEADIPOSITY
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