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The effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on longer-term maternal and early childhood outcomes: protocol for an individual participant data (IPD) meta-analysis

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posted on 2017-03-09, 00:00 authored by Jodie M Dodd, Rosalie M Grivell, Jennie Louise, Andrea R Deussen, Lynne Giles, Ben W Mol, Christina Vinter, Mette Tanvig, Dorte Moller Jensen, Annick Bogaerts, Roland Devlieger, Riitta Luoto, Fionnuala McAuliffe, Kristina Renault, Emma Carlsen, Nina Geiker, Lucilla Poston, Annette Briley, Shakila Thangaratinam, Ewelina Rogozinska, Julie Owens
BACKGROUND: The aim of this individual participant data meta-analysis (IPDMA) is to evaluate the effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood outcomes at ages 3-5 years. METHODS/DESIGN: We will build on the established International Weight Management in Pregnancy (i-WIP) IPD Collaborative Network, having identified researchers who have conducted randomised dietary and lifestyle interventions among pregnant women who are overweight or obese, and where ongoing childhood follow-up of participants has been or is being undertaken. The primary maternal outcome is a diagnosis of maternal metabolic syndrome. The primary childhood outcome is BMI above 90%. We have identified 7 relevant trials, involving 5425 women who were overweight or obese during pregnancy, with approximately 3544 women and children with follow-up assessments available for inclusion in the meta-analysis. DISCUSSION: The proposed IPDMA provides an opportunity to evaluate the effect of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood health outcomes, including risk of obesity. This knowledge is essential to effectively translate research findings into clinical practice and public health policy. SYSTEMATIC REVIEW REGISTRATION: This IPD has been prospectively registered (PROSPERO), ID number CRD42016047165 .

History

Journal

Systematic reviews

Volume

6

Article number

51

Pagination

1 - 12

Publisher

BMC

Location

London, Eng.

eISSN

2046-4053

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2017, The Author(s)