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The platelet intracellular calcium response to serotonin in subsyndromal depression

journal contribution
posted on 1998-05-01, 00:00 authored by Michael BerkMichael Berk, V S Mitchell, H Plein
The relationship of subsyndromal depression to syndromal depression is unclear. Increased sensitivity of platelet serotonin type 2 receptor has been reported in depression using the Fura-2 technique. The sensitivity of the platelet serotonin type 2 receptor was assessed using the Fura-2 method in 16 patients with subsyndromal depression and 14 controls. The patient group had higher numerical values of both basal and serotonin-stimulated levels of platelet intracellular calcium that did not however reach statistical significance.

History

Journal

International clinical psychopharmacology

Volume

13

Issue

3

Pagination

107 - 110

Publisher

Lippincott, Williams & Wilkins

Location

London, Eng.

ISSN

0268-1315

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

1998, Lippincott-Raven Publishers