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The relationship between coronary heart disease (CHD) and major depressive disorder (MDD) : key mechanisms and the role of quality of life
journal contribution
posted on 2013-01-01, 00:00 authored by Adrienne O'NeilVarious trials have been conducted evaluating depression management programs for patients with Coronary Heart Disease (CHD). However, to date, the most effective way to manage this co-morbidity in the real world setting remains unclear. To better understand the past successes and failures of previous trials and subsequently develop suitable interventions that target key components of health related quality of life (HRQOL) such as mental, physical and vocational functioning, we first need to understand the mechanisms underpinning the relationship between the two conditions. This paper will draw on the key literature in this field as identified by psychiatric, medical and social sciences databases (Cochrane Central Register of Controlled Trials, PubMed, OVID, Medline) available up to January 2012, with the aim to conduct a narrative review which explores: the aetiological relationship between depression and CHD; its association with HRQOL; the relationship between CHD, depression and vocational functioning; and the impact of depression treatment on these outcomes. Key recommendations are made regarding the management of this prevalent co-morbidity in clinical settings.
History
Journal
Europe's journal of psychologyVolume
9Issue
1Pagination
163 - 184Publisher
Universitatea din Bucuresti, Asociatia StudentilorLocation
Bucharest, RomaniaISSN
1841-0413Language
engPublication classification
C1 Refereed article in a scholarly journalUsage metrics
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coronary heart diseasecardiovascular diseasemechanismsvocational functioninghealth related quality of lifedepressionSocial SciencesPsychology, MultidisciplinaryPsychologyC-REACTIVE PROTEINCARDIOVASCULAR-DISEASEMYOCARDIAL-INFARCTIONARTERY-DISEASECARDIAC REHABILITATIONRATE-VARIABILITYHEALTH-CAREPSYCHIATRIC-DISORDERSPSYCHOLOGICAL STRESSPLATELET ACTIVATION
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