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The role of genetics in suicide and the link with major depression and alcoholism.

journal contribution
posted on 2000-01-01, 00:00 authored by B Mitchell, D Mitchell, Michael BerkMichael Berk
A clear genetic influence in suicide has been established. In addition, both the serotonergic and noradrenergic systems appear to have a role in suicide, mood disorders and alcoholism. This paper reviews some of the genes that may possibly be involved in suicide and their link to major depression and alcoholism. The genes that are reviewed act on various enzymes within the serotonergic and catecholaminergic systems. With further study, these entities may form a spectrum along the same disease process associated with variable expressivity of the responsible genes.

History

Journal

International Journal of Psychiatry in Clinical Practice

Volume

4

Pagination

275-280

Location

England

ISSN

1471-1788

eISSN

1471-1788

Language

eng

Publication classification

C2.1 Other contribution to refereed journal

Copyright notice

2000, Informa Healthcare

Issue

4

Publisher

Informa Healthcare