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The role of nanomedicine in cell based therapeutics in cancer and inflammation.
journal contribution
posted on 2012-01-01, 00:00 authored by Rasika Samarasinghe, Rupinder Kanwar, Jagat KanwarCell based therapeutics is one of the most rapidly advancing medical fields, bringing together a range of fields including transplantation, tissue engineering and regeneration, biomaterials and stem cell biology. However, traditional cell-based therapeutics have many limitations, one of which is their harmful effects exhibited on healthy body cells due to their lack of specificity. Nanomedicine is providing an alternative treatment strategy that is more targeted and specific to a range of diseases. Varying from polymers conjugated with drugs or tissue targeting molecules, to proteins encapsulated within a polymer shell, nanomedicine will without a doubt play a major role in designing effective cell-based therapeutics that can overcome certain classical problems. These may include from addressing the problem of non-specificity of contemporary treatments to overcoming mechanical barriers, such as crossing cell membranes. This review summarises the recent work on nano-based cell therapy as a regenerative agent and as a therapeutic for cancer and neurological diseases.
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Journal
International journal of molecular and cellular medicineVolume
1Issue
3Season
SummerPagination
133 - 144Publisher
Babol University of Medical SciencesLocation
Babol, IranISSN
2251-9637eISSN
2251-9645Language
engPublication classification
C1.1 Refereed article in a scholarly journalUsage metrics
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