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The zebrafish as a model system for human disease
The zebrafish (Danio rerio) has been widely utilised for the study of developmental biology, which has lead to the evolution of sophisticated cellular and molecular approaches. More recently, the rapid progress of various zebrafish genomic infrastructure initiatives is facilitating the development of zebrafish models of human disease. This review aims to describe several representative examples of how the zebrafish can be successfully used to identify novel genes and assign gene function, providing invaluable clues to human pathophysiology.
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Journal
Frontiers in bioscienceVolume
7Issue
1-3Publisher
Frontiers in BioscienceLocation
Tampa, Fla.Publisher DOI
ISSN
1093-9946eISSN
1093-4715Language
engNotes
Table of contents 1. Abstract 2. Introduction 3. Disease models 3.1. Hematopoietic models 3.2. Renal models 3.3. Cardiac models 3.4. Other developmental diseases 4. Perspective 5. Acknowledgements 6. ReferencesPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2002, Frontiers in BioscienceUsage metrics
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