Deakin University
Browse

File(s) under permanent embargo

Translation and implementation of the Australian-led PCOS guideline: clinical summary and translation resources from the international evidence-based guideline for the assessment and management of Polycystic Ovary Syndrome

journal contribution
posted on 2018-10-01, 00:00 authored by H J Teede, M L Misso, J A Boyle, R M Garad, V McAllister, L Downes, M Gibson-Helm, R J Hart, L Rombauts, L Moran, A Dokras, J Laven, T Piltonen, R J Rodgers, M Thondan, M F Costello, R J Norman, Jane SpeightJane Speight, International PCOS Network
© 2018 AMPCo Pty Ltd. All rights reserved Introduction: We have developed the first international evidence-based guideline for the diagnosis and management of polycystic ovary syndrome (PCOS), with an integrated translation program incorporating resources for health professionals and consumers. The development process involved an extensive Australian-led international and multidisciplinary collaboration of health professionals and consumers over 2 years. The guideline is approved by the National Health and Medical Research Council and aims to support both health professionals and women with PCOS in improving care, health outcomes and quality of life. A robust evaluation process will enable practice benchmarking and feedback to further inform evidence-based practice. We propose that this methodology could be used in developing and implementing guidelines for other women's health conditions and beyond. Main recommendations: The recommendations cover the following broad areas: diagnosis, screening and risk assessment depending on life stage; emotional wellbeing; healthy lifestyle; pharmacological treatment for non-fertility indications; and assessment and treatment of infertility. Changes in management as a result of this guideline: •Diagnosis:▪when the combination of hyperandrogenism and ovulatory dysfunction is present, ultrasound examination of the ovaries is not necessary for diagnosis of PCOS in adult women;▪requires the combination of hyperandrogenism and ovulatory dysfunction in young women within 8 years of menarche, with ultrasound examination of the ovaries not recommended, owing to the overlap with normal ovarian physiology; and▪adolescents with some clinical features of PCOS, but without a clear diagnosis, should be regarded as “at risk” and receive follow-up assessment.•Screening for metabolic complications has been refined and incorporates both PCOS status and additional metabolic risk factors.•Treatment of infertility: letrozole is now first line treatment for infertility as it improves live birth rates while reducing multiple pregnancies compared with clomiphene citrate.

History

Journal

Medical journal of Australia

Volume

209

Issue

S7

Pagination

S3 - S23

Publisher

Wiley

Location

Chichester, Eng.

ISSN

0025-729X

eISSN

1326-5377

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Copyright notice

2018, AMPCo Pty Ltd

Usage metrics

    Research Publications

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC