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Tuneable nanochannel formation for sample-in/answer-out devices

Version 2 2024-06-04, 12:13
Version 1 2017-07-21, 14:09
journal contribution
posted on 2024-06-04, 12:13 authored by AI Shallan, AJ Gaudry, Rosanne GuijtRosanne Guijt, MC Breadmore
Control of the dielectric breakdown of PDMS was achieved by limiting the current during the breakdown process. This enabled tuning of the nanochannel pore size and hence their permeability for molecules of different molecular weights. This method enabled the analysis of the drug quinine from whole blood in 3 min using a simple, disposable microfluidic device.

History

Journal

Chemical communications

Volume

49

Pagination

2816-2818

Location

Cambridge, United Kingdom

eISSN

1364-548X

Language

eng

Publication classification

C Journal article, C1.1 Refereed article in a scholarly journal

Copyright notice

The Royal Society of Chemistry 2013

Issue

27

Publisher

Royal Society of Chemistry