Ultrasensitive DNA detection based on Au nanoparticles and isothermal circular double-assisted electrochemiluminescence signal amplification
journal contribution
posted on 2011-08-07, 00:00 authored by Hong Zhou, Jing Liu, Jing-Juan Xu, Hong-Yuan ChenWe report here an ultrasensitive DNA detection approach which combines Au NPs enhanced electrochemiluminescence (ECL) of the CdS nanocrystal (NC) film with isothermal circular amplification reaction of polymerase and nicking endonuclease (NEase). By the double-signal amplification, this approach could sensitively respond down to 5 aM DNA.
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Journal
Chemical communicationsVolume
47Pagination
8358-8360Location
Cambridge, Eng.ISSN
1359-7345eISSN
1364-548XLanguage
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2011, Royal Society of ChemistryIssue
29Publisher
Royal Society of ChemistryUsage metrics
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