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Zebrafish as a model for leukemia and other hematopoietic disorders

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journal contribution
posted on 2015-01-01, 00:00 authored by Parisa RasighaemiParisa Rasighaemi, Faiza Basheer, Clifford LiongueClifford Liongue, Alister WardAlister Ward
Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.

History

Journal

Journal of hematology & oncology

Volume

8

Issue

29

Pagination

1 - 10

Publisher

BioMed Central

Location

London, Eng.

eISSN

1756-8722

Language

eng

Publication classification

C Journal article; C1 Refereed article in a scholarly journal

Copyright notice

2015, BioMed Central