In this paper, we introduce the concept of “Strategic Digital Information Operations” (SDIOs), discuss the tactics and practices of the SDIOs, explain the main political goals of state and non-state actors in engaging with SDIOs at home and abroad, and suggest avenues for new research. We argue that the concept of the SDIOs presents a useful framework to discuss all forms of digital manipulation at both domestic and international levels organized by either state or non-state actors. While the literature has examined the military-political impacts of the SDIOs, we still don’t know much about societal issues that the SDIOs influence such as emotive political mobilization, intergroup relations, social cohesion, trust, and emotional resonance among target audiences.