A global approach to dissecting lipid-induced impairment of liver gluconeogenesis
thesisposted on 2013-03-01, 00:00 authored by Bradley Hayward
This thesis identified: 1) novel aspects of cholesterol metabolism, 2) a novel signalling lipid in the phosphatidylinositol class, and 3) a gene involved in regulating lipid breakdown, as being regulated in the reversal of a fatty acid induced diabetic liver. The identification of these targets may allow for future development of targeted therapies against type 2 diabetes with a specific focus on the liver.
Paginationxxiii, 268 pages : diagrams, graphs, tables, some coloured