A novel approach to priority-setting for HIV prevention among adults in Uganda

The study used economic and ethical theory, empirical evidence and local stakeholders views to develop a checklist of features of an ideal approach to priority-setting. This was used to determine the ideal approach for priority-setting for HIV prevention in Uganda. The Assessing Cost-Effectiveness (ACE) approach was determined to be the ideal approach using the checklist developed. A pilot study using the approach determined that in Uganda, blood safety and HIV counselling interventions are the most cost-effective, equitable and acceptable interventions. Mass media interventions were the least cost-effective and affordable, had a weak evidence base but were more acceptable. On the other hand interventions targeting Most-at-risk-populations were cost-effective but least acceptable. The study demonstrates the importance of balancing technical rigor and due process to ensure buy-in by stakeholders.