Characterisation and comparison of bovine RNA polymerase III promoters for RNA interference
thesis
posted on 2006-01-01, 00:00authored byLuke Simon. Lambeth
The characterisation of novel bovine RNA polymerase III promoters for the expression of short hairpin RNAs for gene silencing resulted in the identification of a highly efficient promoter sequence. The replication of bovine viral diarrhea virus was them suppressed using short hairpin RNAs expressed form this promoter in vitro.