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Characterisation and comparison of bovine RNA polymerase III promoters for RNA interference

thesis
posted on 2006-01-01, 00:00 authored by Luke Simon. Lambeth
The characterisation of novel bovine RNA polymerase III promoters for the expression of short hairpin RNAs for gene silencing resulted in the identification of a highly efficient promoter sequence. The replication of bovine viral diarrhea virus was them suppressed using short hairpin RNAs expressed form this promoter in vitro.

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thesis

Resource type

thesis

Language

eng

Notes

Degree conferred 2007.

Pagination

xiii, 185 leaves + appendices : ill. ; 30 cm.

Degree name

Ph.D.

Thesis faculty

Faculty of Science

Thesis school

Engineering and Built Environment

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