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Disruption of cytokine signalling in leukemia
thesisposted on 2019-12-18, 00:00 authored by Vilasha Bulleeraz
Mutation of specific genes within the so-called ‘cytokine signalling pathway’ have been identified in blood cancers, including leukemia. This thesis modelled two of these leukemia-related mutations in zebrafish, providing new understanding of their biological effects and creating platforms for future testing of therapeutic agents to combat this lethal disease.