Dissecting ADAMTS proteoglycanase biology in development and disease

Dancevic, C

Dissecting ADAMTS proteoglycanase biology in development and disease

thesis

posted on 2015-08-01, 00:00 authored by C Dancevic

This research was focused upon members of the ADAMTS family of 'proteinases', proteins that have enzymatic activity. Their dysregulation can cause developmental defects and disease. This thesis describes the expression and regulation of ADAMTS15, as well as new developmental functions and inhibition of ADAMTS5 in arthritis.

History

Pagination

xiii, 165 pages : illustrations, some coloured, tables, graphs

Material type

thesis

Resource type

thesis

Language

eng

Degree type

Research doctorate

Degree name

Ph.D.

Copyright notice

The author

Editor/Contributor(s)

C Ward, D McCulloch, Y Gibert

Thesis faculty

Faculty of Health

Thesis school

School of Medicine

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Keywords

ADAMTS proteins arthritis Rheumatology and Arthritis Animal Developmental and Reproductive Biology Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)

Dissecting ADAMTS proteoglycanase biology in development and disease

History

Pagination

Material type

Resource type

Language

Degree type

Degree name

Copyright notice

Editor/Contributor(s)

Thesis faculty

Thesis school

Usage metrics

Categories

Keywords

Licence

Exports