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Dissecting ADAMTS proteoglycanase biology in development and disease

thesis
posted on 2015-08-01, 00:00 authored by C Dancevic
This research was focused upon members of the ADAMTS family of 'proteinases', proteins that have enzymatic activity. Their dysregulation can cause developmental defects and disease. This thesis describes the expression and regulation of ADAMTS15, as well as new developmental functions and inhibition of ADAMTS5 in arthritis.

History

Pagination

xiii, 165 pages : illustrations, some coloured, tables, graphs

Material type

thesis

Resource type

thesis

Language

eng

Degree type

Research doctorate

Degree name

Ph.D.

Copyright notice

The author

Editor/Contributor(s)

C Ward, D McCulloch, Y Gibert

Faculty

Faculty of Health

School

School of Medicine