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Dissecting the role of SOCS proteins using zebrafish

thesis
posted on 2008-01-01, 00:00 authored by Lynda Anne. O'Sullivan
Suppressors of cytokine signalling (SOCS) proteins are negative regulators of the JAK-STAT pathway which is perturbed in certain disease states including cancers and inflammatory diseases. This thesis ascertained the suitability of zebrafish as an alternative animal model to study the SOCS proteins which established new and additional roles during development.

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Pagination

xv, 180 leaves : ill. ; 30 cm.

Material type

thesis

Resource type

thesis

Language

eng

Notes

Degree conferred 2009.

Degree name

Ph.D.

Faculty

Faculty of Science

School

Engineering and Built Environment

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