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Evolution of class I cytokine receptor signalling : conservation of GCSFR
thesisposted on 2008-01-01, 00:00 authored by Clifford. Liongue
Cytokines are proteins that provide essential signals to blood and immune cells. The evolution of this system was determined from primitive organisms to humans and zebrafish. Analysis of zebrafish granulocyte colony-stimulating factor (GCSF) signalling revealed broad conservation of function with mammals and a novel role in white blood cell migration.