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Harnessing intracellular signalling to develop a functional bioassay for anti Interleukin-17 antibody

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posted on 2023-07-28, 04:04 authored by Sravana Kumar Pulipati
This study addressed IL-17 induced TNBC cell invasion in vitro. This study identified that IL-17 down regulates surface expression of B3-integrin and induces IL-1B secretion. Some of these novel findings were backed by published work of parallel researchers. These findings emphasize on IL-17 induced anoikis resistance mechanisms and downstream functions of IL-1B in IL-17A driven invasion mechanisms in TNBC cells.

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326 p.

Open access

  • Yes

Language

English

Degree type

Doctorate

Degree name

Ph.D.

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All rights reserved

Editor/Contributor(s)

Jagat Kanwar, Rupinder Kanwar, Venkata Ramana, Arnab Kapat, Abbas Kouzani

Faculty

Faculty of Health

School

School of Medicine

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