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Ikaros gene family : characterisation of the 'atypical' Pegasus

thesis
posted on 2010-01-01, 00:00 authored by Liza Bernadine John
Ikaros-related transcription factors are essential for adaptive immunity. Evolutionary analysis suggested derivation from a precursor similar to the 'atypical' Pegasus protein, and possibly related to invertebrate Hunchback. Pegasus was shown to regulate neural, gut and blood cell development in zebrafish, with Ikaros identified as one of several potential gene targets.

History

Pagination

xix, 221 leaves : ill. ; 30 cm.

Material type

thesis

Resource type

thesis

Language

eng

Notes

Thesis (Ph.D.)--Deakin University, Victoria, 2010.

Degree name

Ph.D.

Faculty

Faculty of Health

School

School of Medicine