Investigation of JAK/STAT signaling in human skeletal muscle
thesis
posted on 2009-01-01, 00:00 authored by Marissa K. TrenerryUnderstanding muscle adaptation and repair is vital for preserving muscle loss with aging. Analysis of the inflammatory-responsive signalling pathway, JAK/STAT was performed. After intense exercise, the STAT3 pathway is highly activated, potentially by the pro-inflammatory regulator IL-6. This pathway is suppressed in older individuals, possible leading to altered inflammatory regulation.
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xviii, 131 p ; 30 cm.Material type
thesisResource type
thesisLanguage
engNotes
Degree conferred 2010.Degree name
Ph.D.Faculty
Faculty of HealthSchool
School of Exercise and Nutrition SciencesUsage metrics
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