Deakin University
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Mohanasundaram-mappingthe-2016A.pdf (10.49 MB)

Mapping the genotype-phenotype relationship in complex disease.

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thesis
posted on 2016-04-01, 00:00 authored by K Mohanasundaram
Computational methods to identify harmful variations in humans perform well for rare diseases such as Huntington's but not for common diseases like hypertension or diabetes. A modelling approach that takes protein context into account was illustrated to identify harmful variants involved in complex diseases.

History

Pagination

xvii, 221 pages : tables, figures, some coloured.

Open access

  • Yes

Material type

thesis

Resource type

thesis

Language

eng

Degree type

Research doctorate

Degree name

PhD.

Copyright notice

The Author. All Rights Reserved

Editor/Contributor(s)

M Wouters, T Crowley Tamsyn

Faculty

Faculty of Health

School

School of Medicine