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Novel secreted proteins involved in obesity and type 2 diabetes
thesisposted on 2007-01-01, 00:00 authored by Kristy. Bolton
A signal sequence trap was utilised to identify secreted proteins which were differentially expressed in key metabolic tissues associated with obesity and type 2 diabetes. Decorin and periostin were identified and functionally characterised as novel secreted proteins associated with the pathophysiology of these conditions.