Synthesis of flavonoids and flavonoid-based designed multiple ligands for hypertension

The flavonoids, a family of compounds found in nature, possess a wealth of established health benefits. In this research, a library of novel flavonoid compounds was synthesised for therapeutic evaluation. A particular focus was the attachment of 3ʹ,4ʹ-dihydroxyflavonol, an antioxidant and antihypertensive flavonoid, to other known antihypertensives, to provide dual action compounds for the treatment of hypertension.